Adrenaline Doesn’t Actually Cause the Fight-or-Flight Response, New Study Says

By Jennifer Walter
Sep 12, 2019 12:00 AMNov 19, 2019 12:30 AM
Fight-or-Flight
When you’re overcome with fear, it’s not adrenaline making you want to fight or flee. (Credit: Master1305/Shutterstock)

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A thrilling high when you’re faced with danger, a boost of energy when you’re going for an intense run – we tend to associate these rushes with adrenaline, a hormone synonymous with our fight-or-flight response. But it turns out adrenaline might not be what activates our brains’ stress reaction after all.

In fact, our bones might be doing more work than we originally thought. A new study, published today in Cell Metabolism, finds that adrenaline is just one component of our response to stress. Of perhaps greater importance in life-or-death situations is a hormone called osteocalcin, which is secreted by our bones.

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