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Female Hormones Help the Body Produce Its Own Opioids to Handle Pain

Studying how the different sexes manage pain could lead to better treatments for pain conditions.

ByJenny Lehmann
Lymphocytes such as T cells. (Image Credit: ART-ur/Shutterstock)

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It’s no secret that women and men experience pain differently, and there are a variety of reasons to cause this variance in pain perception. Hormones are known to influence pain sensitivity, body structure affects the density of pain receptors, and psychological and social factors play a role in how pain is perceived and expressed.

With all these factors in mind, it’s surprising to learn that most pain research has historically ignored sex differences. As a result, many studies missed the opportunity to analyze or report these differences. The impact of this gender bias in pain research is clear: Women often struggle more than men to be taken seriously and treated appropriately, according to the International Association for the Study of Pain.

Fortunately, research is improving. Today, studies are asking more questions and including female participants in both preclinical and clinical research. A recent study from University of California San Francisco, ...

  • Jenny Lehmann

    Having worked as a biomedical research assistant in labs across three countries, Jenny excels at translating complex scientific concepts – ranging from medical breakthroughs and pharmacological discoveries to the latest in nutrition – into engaging, accessible content. Her interests extend to topics such as human evolution, psychology, and quirky animal stories. When she’s not immersed in a popular science book, you’ll find her catching waves or cruising around Vancouver Island on her longboard.

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