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Treating a Viral Infection in Cats May Solve the Mystery of Long COVID

Learn about the disease in cats that shows striking similarities to long COVID and the treatment that can restore feline immune dysfunction.

Jack Knudson
ByJack Knudson
Leo, a 10-month-old tabby cat, is cared for by Clinical Trials Coordinator Jully Pires after receiving treatment as part of a clinical trial on FIP at UC Davis School of Veterinary Medicine. (School of Veterinary Medicine)Image Credit: UC Davis School of Veterinary Medicine

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Some people who’ve suffered through COVID-19 never quite feel 100 percent, stuck in the throes of a medical mystery centered around an impaired immune system. Long COVID isn’t fully understood yet, but scientists are closing in on crucial clues by investigating a similar phenomenon in cats.

A new study published in Stem Cells Translational Medicine explains how a relatively rare feline disease is almost like a cat version of long COVID. Similar to severe coronavirus infections in humans, feline infectious peritonitis (FIP) sends cats’ immune system off-kilter. Therapy involving mesenchymal stromal cells, however, has shown promise in restoring immune function in cats, potentially serving as a blueprint for long COVID research.

FIP in cats starts out as feline coronavirus, a common viral infection that infects the cells lining a cat’s intestines and leads to mild stomach issues. But a mix of genetic and environmental circumstances can occasionally change the virus’s ...

  • Jack Knudson

    Jack Knudson

    Jack Knudson is an assistant editor for Discover Magazine who writes articles on space, ancient humans, animals, and sustainability, and manages the Planet Earth column of the print issue.

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