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NCBI ROFL: Bad news: you have a tumor. Good news: it's really cute!

Explore amusing 'images in pathology' where pathologists find whimsical shapes in biopsies, including a puppy and a smiling bone.

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Pathologists must get bored staring at tumors all day, so they start imagining little friends in their samples. There are numerous papers in PubMed highlighting their "discoveries" (or perhaps the results of self-imposed Rorschach tests?)

. Here are five of our favorites:

Nonproliferative Fibrocystic Changes and the Easter Bunny

"A 46-year-old woman had an excisional breast biopsy that revealed nonproliferative fibrocystic changes as the only histopathologic abnormality. Although it was not Easter at the time of diagnosis, an Easter bunny was found hiding in one of the dilated ducts, which also contained amorphous eosinophilic secretions. A benign diagnosis in a breast biopsy (or any other biopsy) is good news for the patient at any time of the year, but even more special when accompanied by this little fellow."

Images in pathology. Invasive squamous cell carcinoma of vulva that wanted to be a puppy. "Squamous cell carcinomas of the vulva are ...

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