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Stephen Hawking's Disease: How ALS Impacts the Body and Progress for Treatment

Learn more about ALS, the disease that affected Stephen Hawking, and the advances made to find a cure.

ByEmilie Le Beau Lucchesi
Stephen Hawking lived for decades with ALS, also known as Lou Gehrig’s disease. (Koca Vehbi/Shutterstock) null

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ALS stands for amyotrophic lateral sclerosis and is also known as Lou Gehrig's disease.

Stephen Hawking lived with ALS for 55 years and advocated for research and helped bring awareness to the disease.

ALS is fatal, and impacts a person's ability to talk, eat, walk, and breath. Progress for treatment includes a genetic treatment, Qalsody, that was approved by the Federal Drug Administration (FDA) in 2023.

In 1939, Lou Gehrig, the first baseman for the New York Yankees, shocked the baseball world when he benched himself mid-season after playing 2,130 consecutive games. Though he'd had a stellar season the year prior, something was different. He didn't know it quite yet, but he was beginning to experience the symptoms of amyotrophic lateral sclerosis (ALS). Doctors diagnosed Gherig on his 36th birthday, and he passed away just before his 38th.

Renowned physicist Stephen Hawking was diagnosed with ALS (also known as Lou ...

  • Emilie Le Beau Lucchesi

    Emilie Lucchesi has written for some of the country's largest newspapers, including The New York Times, Chicago Tribune and Los Angeles Times. She holds a bachelor's degree in journalism from the University of Missouri and an MA from DePaul University. She also holds a Ph.D. in communication from the University of Illinois-Chicago with an emphasis on media framing, message construction and stigma communication. Emilie has authored three nonfiction books. Her third, A Light in the Dark: Surviving More Than Ted Bundy, releases October 3, 2023, from Chicago Review Press and is co-authored with survivor Kathy Kleiner Rubin.

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