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Peyote vs. Ayahuasca: What Is the Difference?

What are the differences between the Peyote and Ayahuasca plants? Both are known for their ability to alter states of consciousness, and could become a form of therapy.

ByMatt Hrodey
Harvested peyote that a person can ingest for psychedelic experiences.Credit: Photo Spirit/Shutterstock

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At first glance, the peyote and ayahuasca plants may seem similar, but a closer look reveals the intricacies that set them apart. Are they, in fact, the same thing, or do they belong to entirely separate realms?

Learn the unique differences between the side effects and origins of the peyote and ayahuasca plants, two powerful conduits to altered states of consciousness.

Harvested peyote that a person can ingest for psychedelic experiences. (Credit: Photo Spirit/Shutterstock)

Photo Spirit/Shutterstock

Peyote, a thornless cactus, contains the psychoactive compound known as mescaline as its primary hallucinogenic component. Its bitter buttons, which cluster around a central flower, can be eaten raw or dried (crunchy like potato chips) or steeped to make tea.

As a vestige of 1960s drug policy, peyote and mescaline remain Schedule I controlled substances, like heroin and LSD.

Huxley’s account of his experience, 1954’s The Doors of Perception, popularized psychedelic experimentation in general ...

  • Matt Hrodey

    Matt is a staff writer for DiscoverMagazine.com, where he follows new advances in the study of human consciousness and important questions in space science - including whether our universe exists inside a black hole. Matt's prior work has appeared in PCGamesN, EscapistMagazine.com, and Milwaukee Magazine, where he was an editor six years.

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