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MRI Killed The Radiotracer

Discover why Positron Emission Tomography's influence in neuroscience research has declined dramatically over the years.

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Positron Emission Tomography (PET) was once among the most powerful techniques available for researching human brain activity. By injecting a volunteer with a radioactive tracer, such as a glucose derivative, and monitoring the radiation emitted from the brain over the next few hours, neuroscientists could see where in the brain most glucose was being absorbed - and where neural activity was happening. But in recent years, the influence of PET in neuroscience research has fallen dramatically, as shown in a new paper by Neuroimage assistant editor Paul Cumming: PET Neuroimaging: The White Elephant Packs His Trunk? Here's the numbers of research papers published per year (note the exponential scale.)

PET studies of the brain have been declining since about 1985, despite the fact that research about the brain in general has grown. It seems it was fMRI scanning that killed PET. Cheaper, safer (no radiation), and more versatile, the growth ...

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