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Leprosy Reborn: How a Long-maligned Disease Might Unlock the Secrets of Stem Cells

Anura Rambukkana's leprosy research reveals how Mycobacterium leprae manipulates cells, potentially advancing nerve regeneration techniques.

The leprosy bacteria.Credit: Kateryna Kon/Shutterstock

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For the past 25 years, Anura Rambukkana has been studying a disease that’s already been cured. He studies leprosy, a disease that was once the scourge of humanity before a course of drugs developed in the mid-20th century brought it under control.

For decades, he’s worked in a field that sees little funding and few new faces, and many of his contemporaries have moved on to higher-profile projects involving diseases that attract grant dollars. Rambukkana, a professor of regeneration biology at the Centre for Regenerative Medicine at the University of Edinburgh, likely would have joined them, but for a singular captivation by the leprosy bacterium — and the hunch that it might have something to teach us.

Anura Rambukkana. (Credit: University of Edinburgh)

University of Edinburgh

Anura Rambukkana. (Credit: University of Edinburgh)

Working as a graduate student in Amsterdam analyzing skin samples from leprosy patients, he picked up on an ...

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