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Is Medical Science Really 86% True?

Exploring false positive p values reveals skepticism around results in medical literature findings—only 14% might be wrong.

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The idea that Most Published Research Findings Are False rocked the world of science when it was proposed in 2005. Since then, however, it's become widely accepted - at least with respect to many kinds of studies in biology, genetics, medicine and psychology.

Now, however, a new analysis from Jager and Leek says things are nowhere near as bad after all: only 14% of the medical literature is wrong, not half of it. Phew!

But is this conclusion... falsely positive?

I'm skeptical of this result for two separate reasons. First off, I have problems with the sample of the literature they used: it seems likely to contain only the 'best' results. This is because the authors:

only considered the

creme-de-la-creme

of top-ranked medical journals, which may be more reliable than others.

only looked at the Abstracts of the papers, which generally contain the best results in the paper.

only included ...

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