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Difficulty Reaching REM Sleep May Signal Early Warning for Alzheimer’s

Study showed that patients who took longer to reach the dream state also had more biomarkers for the disease.

ByPaul Smaglik
(Credit: Pormezz/Shutterstock) Pormezz/Shutterstock

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Researchers studying the science of sleep are building a growing body of evidence connecting both the quantity and quality of slumber to the risk of developing Alzheimer’s disease.

Now a group shows that people who take longer to enter the dream phase of sleep known as rapid eye movement (REM) may be exhibiting an early symptom of the disease, according to work published in Alzheimer’s and Dementia: The Journal of the Alzheimer's Association.

The results have implications for three groups: people concerned about their Alzheimer’s risk, doctors who diagnose and treat the disease, and researchers who study sleep.

For that first group, Yue Leng, a psychiatry professor at the University of California, San Francisco, and an author of the study, has a simple message: “You really, really need to pay attention to your sleep,” she says.

Researchers don’t yet know whether someone’s difficulty entering REM is only a diagnostic tool ...

  • Paul Smaglik

    Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American.

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