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Could Ozempic Be the Next Breakthrough in Addiction Treatment?

Experts are looking into using Ozempic as a possible medication to curb cravings. What could the latest research mean for addiction?

ByMatt Hrodey
New medications could work by interrupting the reward circuit in the brain.Credit: simon jhuan/Shutterstock

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Alcohol use disorder, the medical diagnosis for alcoholism, affects about 10 percent of the U.S. population, or 29.5 million people. Yet, doctors wanting to treat this condition have only a handful of medications at their disposal, including such drugs as disulfiram, Acamprosate and naltrexone.

Disulfiram makes people violently ill if they drink. Acamprosate is powerfully tranquilizing. And naltrexone suppresses the opioid system, which can reduce cravings in both alcoholics and opiate users. Still, doctors rarely prescribe these drugs, as only about 5 percent of patients in the U.S. take one of them.

They’re often seen as inferior to the life-changing psychosocial interventions (professional treatment and 12-step programs) normally recommended. But experts are now looking into the use of Ozempic as a form of medication in the treatment of addiction.

They’re called GLP-1 agonists, and they include the popular diabetes drug Ozempic – heavily prescribed off-label for weight loss – and ...

  • Matt Hrodey

    Matt is a staff writer for DiscoverMagazine.com, where he follows new advances in the study of human consciousness and important questions in space science - including whether our universe exists inside a black hole. Matt's prior work has appeared in PCGamesN, EscapistMagazine.com, and Milwaukee Magazine, where he was an editor six years.

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