Regular readers will be familiar with the idea that "antidepressants only work in severe depression".
A number of recent studies have shown this. I've noted some important questions over how we ought to define "severe" in this context, and see the comments here for some other caveats, but I'm not aware of any studies that directly contradict this idea.
Until now. A new paper has just come out which seeks to challenge this dogma - not the author's term, but I think it's fair to say that the severity theory is becoming a dogma, even if it's an evidence-based one (but then, all dogmas start out seeming reasonable).
However, while the new paper is interesting, I think the dogma survives intact.
The authors went through the archives of all of the trials of antidepressants for depressive disorders conducted at the famous New York State Psychiatric Institute for the past 30 ...
