From the text of John Holdren's recent congressional testimony on the science budget (also available here):
All told, this Budget proposes $66.8 billion for civilian research and development, an increase of $4.1 billion or 6.5 percent over the 2010 funding level in this category. But the Administration is committed to reducing the deficit even as we prime the pump of discovery and innovation. Accordingly, our proposed investments in R&D, STEM education, and infrastructure fit within an overall non-security discretionary budget that would be frozen at 2010 levels for the second year in a row. The Budget reflects strategic decisions to focus resources on those areas where the payoff for the American people is likely to be highest.
This is similar to what I argued with Meryl Comer in the Los Angeles Times in December--tough economic times are the times to invest in science, not cut it. Holdren concludes:
Let me ...