The Truth About Truth Serum

It doesn’t actually exist, but plenty of drugs are purported to ferret out the facts. These methods, sometimes used in law enforcement, raise scientific and ethical questions.

By Cody Cottier
Oct 3, 2021 5:00 AMOct 3, 2021 6:01 PM
truth serum brain medication drops
Law enforcement officials have long used drugs like barbiturates to interrogate suspects. (Credit: Valery Brozhinsky/Shutterstock)

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The ability to separate truths from falsehoods has long evaded humanity: We’re prone to lying when it behooves us, and we do a poor job of recognizing when we’re the ones being lied to. Even police officers and other specialists trained in the detection of deceit fall short about as often as the average person

One sought-after solution is the fabled “truth serum,” a generic term for any drug that renders its recipient incapable of telling a lie. Currently, no such drug exists — that is, none that consistently and predictably induce truth-telling. Nevertheless, this power has been attributed to a host of concoctions in the past century. These claims have fueled debate over their ethics and legality, as well as the mechanisms behind memory itself.

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