Another paper with another technique to detect positive selection in the human genome, Identification of local selective sweeps in human populations since the exodus from Africa:
Selection on the human genome has been studied using comparative genomics and SNP architecture in the lineage leading to modern humans. In connection with the African exodus and colonization of other continents, human populations have adapted to a range of different environmental conditions.
Using a new method that jointly analyses haplotype block length and allele frequency variation (F(ST)) within and between populations
, we have identified chromosomal regions that are candidates for having been affected by local selection. Based on 1.6 million SNPs typed in 71 individuals of African American, European American and Han Chinese descent, we have identified a number of genes and non-coding regions that are candidates for having been subjected to local positive selection during the last 100 000 years. Among ...
