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Using cannabinoids to overcome fear in the brain

Explore how the fear response connects brain chemistry and anxiety disorders, hinting at new therapeutic pathways.

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We all know exactly what fear feels like. Without our consent, our hearts begin to beat a little faster. The hairs on the back of our neck prickle. Our palms sweat through clenched fingers. Fear is so much more than an emotion; it is a whole body experience. But it doesn't start that way - it starts in our brains. When we sense danger or threat, a signal is sent to the walnut sized structure in our forebrains called the amygdala, which is responsible for alerting the rest of our body to prepare for fight or flight. Once the threat is removed, the signal relaxes, and so do we. But for those who suffer from anxiety disorders, it takes much longer for the brain to sound the all clear. "We've learned a fair amount of the circuitry that's involved in generating the initial fear response. We really know relatively little ...

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