This Medication Could Make Human Blood Deadly to Mosquitos, Combatting Malaria

Discover nitisinone, a drug for rare diseases that could also combat mosquitoes and their transmission of malaria.

By Sam Walters
Mar 26, 2025 9:30 PMMar 26, 2025 9:26 PM
Glow-in-the-dark Mosquito
An Anopheles gambiae mosquito that has been fed dye to make her glow. (Image Credit: Lee R. Haines)

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Mosquitoes are more than pests. They’re also a mortal threat, contributing to millions of cases of malaria a year. Fortunately for humans, however, a team of researchers has recently identified a medication that could curb mosquito populations, controlling their spread of malaria.

Revealing their results in a paper published in Science Translational Medicine, the researchers report that the medication nitisinone makes human blood deadly to mosquitoes.

“One way to stop the spread of diseases transmitted by [mosquitoes] is to make the blood of animals and humans toxic to these blood-feeding insects,” said Lee R. Haines, a paper author and an associate research professor of biology at the University of Notre Dame, according to a press release. “Our findings suggest that using nitisinone could be a promising new complementary tool for controlling insect-borne diseases like malaria.”


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