Register for an account

X

Enter your name and email address below.

Your email address is used to log in and will not be shared or sold. Read our privacy policy.

X

Website access code

Enter your access code into the form field below.

If you are a Zinio, Nook, Kindle, Apple, or Google Play subscriber, you can enter your website access code to gain subscriber access. Your website access code is located in the upper right corner of the Table of Contents page of your digital edition.

Health

Synthetic associations and all that

Gene ExpressionBy Razib KhanJanuary 19, 2011 1:28 AM

Newsletter

Sign up for our email newsletter for the latest science news

PLoS Biology has four items of great interest out today: - Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS ResultsSynthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association SignalsThe Importance of Synthetic Associations Will Only Be Resolved EmpiricallyCommon Disease: Are Causative Alleles Common or Rare? These are a response to last year's paper on synthetic associations from the Goldstein lab. Here's a critique of that that paper. I plan on reviewing the first in the list above soon. #3 is a response to #1 and #2 from David Goldstein, while #4 is a summation more aimed at the general audience.

    2 Free Articles Left

    Want it all? Get unlimited access when you subscribe.

    Subscribe

    Already a subscriber? Register or Log In

    Want unlimited access?

    Subscribe today and save 70%

    Subscribe

    Already a subscriber? Register or Log In