Stephen Hawking's Disease: How ALS Impacts the Body and Progress for Treatment

Learn more about ALS, the disease that affected Stephen Hawking, and the advances made to find a cure.

By Emilie Le Beau Lucchesi
May 19, 2025 1:00 PM
Stephen Hawking lived for decades with ALS, also known as Lou Gehrig’s disease
Stephen Hawking lived for decades with ALS, also known as Lou Gehrig’s disease. (Koca Vehbi/Shutterstock)

Newsletter

Sign up for our email newsletter for the latest science news
 

Key Takeaways on ALS, or Stephen Hawking's Condition:

  • ALS stands for amyotrophic lateral sclerosis and is also known as Lou Gehrig's disease.

  • Stephen Hawking lived with ALS for 55 years and advocated for research and helped bring awareness to the disease.

  • ALS is fatal, and impacts a person's ability to talk, eat, walk, and breath. Progress for treatment includes a genetic treatment, Qalsody, that was approved by the Federal Drug Administration (FDA) in 2023.


In 1939, Lou Gehrig, the first baseman for the New York Yankees, shocked the baseball world when he benched himself mid-season after playing 2,130 consecutive games. Though he'd had a stellar season the year prior, something was different. He didn't know it quite yet, but he was beginning to experience the symptoms of amyotrophic lateral sclerosis (ALS). Doctors diagnosed Gherig on his 36th birthday, and he passed away just before his 38th.

Renowned physicist Stephen Hawking was diagnosed with ALS (also known as Lou Gehrig's disease) in 1963. However, doctors were still unsure what caused the disease and if there were any possible treatments. Hawking's doctors gave him about two years to live, however, he lived with the disease for 55 years.

0 free articles left
Want More? Get unlimited access for as low as $1.99/month

Already a subscriber?

Register or Log In

0 free articlesSubscribe
Discover Magazine Logo
Want more?

Keep reading for as low as $1.99!

Subscribe

Already a subscriber?

Register or Log In

Stay Curious

Sign up for our weekly newsletter and unlock one more article for free.

 

View our Privacy Policy


Want more?
Keep reading for as low as $1.99!


Log In or Register

Already a subscriber?
Find my Subscription

More From Discover
Stay Curious
Join
Our List

Sign up for our weekly science updates.

 
Subscribe
To The Magazine

Save up to 40% off the cover price when you subscribe to Discover magazine.

Copyright © 2025 LabX Media Group