Stay Curious

SIGN UP FOR OUR WEEKLY NEWSLETTER AND UNLOCK ONE MORE ARTICLE FOR FREE.

Sign Up

VIEW OUR Privacy Policy


Discover Magazine Logo

WANT MORE? KEEP READING FOR AS LOW AS $1.99!

Subscribe

ALREADY A SUBSCRIBER?

FIND MY SUBSCRIPTION
Advertisement

"Metabolic Sins of the Father": Fat Dads May Give Their Kids Diabetes

Discover the 'fat father effect'—how a father's diet may influence his daughters' insulin resistance across generations.

Newsletter

Sign up for our email newsletter for the latest science news

Sign Up

Scientists knew that overweight mothers tend to have more overweight children. But is the same true for fathers? This week in Nature, Margaret Morris and her team demonstrated this effect in male rats, the first time it's been shown to work in males. The findings are another example of how non-genetic factors, like how much a parent eats, can have a biological impact on offspring. The researchers put one of their two groups of male rats on a high-fat diet, the other on a normal one. Unsurprisingly, the high-fat rats put on a lot of weight and began to show symptoms of type II diabetes, like insulin resistance and struggles with metabolizing glucose. And then there were their kids:

The real surprise came when Morris's team went on to examine the obese rats' female offspring. These too had problems regulating insulin and glucose levels. The healthy fathers, however, had correspondingly ...

Stay Curious

JoinOur List

Sign up for our weekly science updates

View our Privacy Policy

SubscribeTo The Magazine

Save up to 40% off the cover price when you subscribe to Discover magazine.

Subscribe
Advertisement

0 Free Articles