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How Ritalin Works in the Brain: With a One-Two Dopamine Punch

Ritalin boosts learning speed by enhancing dopamine, revealing its potential as a smart pill for students.

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College students holed up in the library or cramming for an exam have always relied on stimulants like coffee, but recently they’ve been increasingly turning to the off-label use of drugs like Ritalin and Modafinil to help them stay focused. Now scientists have found how Ritalin, a drug normally prescribed for children with attention deficit hyperactivity disorder (ADHD), helps boost learning.

In a new study of rats published online in Nature Neuroscience, scientists found that Ritalin appears to boost both attention and enhance the speed of learning by increasing the activity of the chemical messenger dopamine [Technology Review]. The study also found that one type of dopamine receptor aids the ability to focus, and another type improves the learning itself [DNA].

In their study, scientists observed that rats on Ritalin learned faster than those not given the drug; the Ritalin-drugged rats understood more quickly that a flash of light and ...

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