Timposts on the recent PLOS paper Gene Losses during Human Origins published by the Wang et al. If that gets you all excited, check out The Origin of Subfunctions and Modular Gene Regulation and Preservation of Duplicate Genes by Complementary, Degenerative Mutations. I might lionize the contributions of R.A. Fisher, Sewall Wright and J.B.S. Haldane to evolutionary biology, but as I posted before, tools need tasks, and the mass of data being unveiled by genomics is uncovering many surprises. Science isn't about a priori inference, it is about venturing into the wilds, and by the grace of god we live in an Age of Discovery (the post-genomic era).