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Blind mice regain sight after scientists persuade their optic nerves to grow

Discover the latest breakthroughs in optic nerve regeneration that could restore vision for those with optic nerve damage.

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A mouse optic nerve with new axons (in red) running all the way along it.

A blind man sees his fiancée’s smile for the first time. Another walks around at night, navigating via streetlamps and headlights. Yet another reads his own name (and spots a typo). All three had lost their sight years before, as an inherited disorder destroyed the light-sensing cells of their retinas. But they had since been fitted with retinal implants

that took over from the broken cells, sensing incoming light, and converting it into electrical impulses delivered to the brain. The devices are a long way from 20/20 vision, but they have nonetheless restored sight to those who had lived without it for years. These retinal implants seem miraculous, but they have a major drawback: they rely upon a working optic nerve. This is the main communication line between the eye and the brain. If it’s ...

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