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A Molecule That Can Help Antibiotics Kill Superbugs

Discover how Klebsiella pneumoniae resistance challenges healthcare and the latest adjuvant to boost antibiotic efficacy.

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K. pneumoniae

Bacteria that have evolved defenses against antibiotics are something of a disaster waiting to happen. Whenever a new drug-resistant strain, or a gene that confers resistance, crops up in a new place---as when the NDM-1 gene, which confers resistant to up to 14 drugs, showed up in drinking water in New Delhi

---it's another nail in coffin of a world in which we can heal nearly everything. Scientists are looking into how to get around that resistance, though, and there are some hopeful headlines now and then, including a recent study

from researchers at North Carolina State University in which they identified a molecule that can boost the efficacy of two antibiotics against bacteria 16-fold. The molecule, which the researchers found by testing about 50 candidates to see if they could reduce the number of NDM-1-carrying K. pneumoniae

by a significant amount, doesn't have any antimicrobial properties of ...

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