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10 Weird, Wacky and Worthwhile Experiments

Unexpected and offbeat discoveries sometimes yield the most startling advances in medical science.

Stapp’s wild ride: The intrepid flight surgeon endures a 1954 rocket sled ride that took him from zero to over 400 mph in just five seconds. (Keystone/Hulton Archive/Getty Images)

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The medical record is surprisingly rich with bumbles and quirks, bold moves and devil-may-care experimentation. But important and interesting discoveries have come from these often outrageous acts: by sheer accident, through daring self-sacrifice, from people eccentric enough to look at medical issues through an equally unconventional perspective.

Here’s a look at 10 successes from the annals of the avant-garde that actually worked, along with a brief analysis of their continuing impact on areas as diverse as heart disease, pain management, gastroenterology and seat belts.

This Is Spinal Tap: The Bizarre Origins of Epidurals

German surgeon August Bier remains best known for two things: First, the quote “A professor is a gentleman with a different point of view.” Second, the way he embodied that different point of view while pioneering spinal anesthesia as a surgical procedure.

Inspired by the work of New York neurologist James Corning, who experimented with injections of ...

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