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Painkilling chemicals with no side effects found in black mamba venom

Discover how black mamba venom yields mambalgins, revolutionary pain relief proteins that rival morphine without toxic side effects.

Black_mamba

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The black mamba has a fearful reputation, and it’s easy to see why. It can move at around 12.5 miles (20 kilometres) per hour, making it one of the world’s fastest snakes, if not the fastest. Its body can reach 4.5 metres in length, and it can lift a third of that off the ground. That would give you an almost eye-level view of the disturbingly black mouth from which it gets its name. And inside that mouth, two short fangs deliver one of the most potent and fast-acting venoms of any land snake.

Combined with its reputation for aggression (at least when cornered) and you’ve got a big, intimidating, deadly, ornery serpent that can probably outrun you. It’s not the most obvious place to go looking for painkillers.

But among the cocktail of chemicals in the black mamba’s venom, Sylvie Diochot and Anne Baron from the CNRS have found ...

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