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The importance of open data in genomics (and in everything!)

Explore how to verify Sub-Saharan African ancestry using raw data analysis for accurate genetic information interpretation.

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Yesterday a friend of mine who happens to be of doughty German and Scandinavian upper Midwest stock messaged me on Facebook and explained that her father's results for 23andMe had come in...and he was 43 percent Sub-Saharan African! Her mother's results came in a few hours later, and she was 35 percent Sub-Saharan African. I went to my account, and my parents were also in the same range. Oh my, overnight I became an underrepresented minority! Obviously this was a bug. The key clause is obviously. There are people who receive results suggesting that they are 5 percent Sub-Saharan African and such. Or someone like Dan MacArthur, who has likely South Asian ancestry, but in the 1-2 percent range. How do you know that these results are not bugs? You analyze the raw data. Those who have skills with Plink or Admixture can double check easily, as I did with ...

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