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Making Pig Stem Cells Raises the Possibility of Animal Organ Donors

Discover how genetically engineered pigs and stem cells could revolutionize organ donation and xenotransplantation potential.

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It was only a few years ago that scientists figured out how to reprogram adult cells to make them act like multipurpose stem cells, but the next discoveries are coming fast and furious. Researchers had previously transformed human skin cells into so-called induced pluripotent stem (iPS) cells that can grow into any type of tissue; now, a new study reports that the same feat has been accomplished with pig cells. The achievement raises the possibility that genetically engineered pigs could be reared as organ donors, researchers say. The created iPS cells could be genetically altered, and then cloned to produce pigs with certain traits.

By adding or deleting certain genes, for example, researchers could produce pigs whose organs can be transplanted into patients without them being recognised and rejected. Efforts to do such xenotransplants have already been under way for at least a decade, but iPS cells are easier to ...

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