[
This is the first of three intertwined posts on PKMzeta - the molecule that keeps our memories intact
]
We’re used to the idea that we become more forgetful with age. As time passes, our memories naturally fade and weaken, and that’s if we’re lucky enough to avoid traumatic accidents or diseases like Alzheimer’s. But Reut Shema
, from the Weizmann Institute of Science in Israel, has found a possible way of preventing this decline, and even reversing it. By loading the brains of rats with a protein called PKMzeta, she managed to strengthen their memories, even old and faded ones. “Multiple old memories were robustly enhanced. These results have no precedent,” says Todd Sacktor
, who led the study together with Yadin Dudai
. PKMzeta is the engine of memory. This single protein behaves like a machine that constantly works to keep our memories intact. Switch it off, ...