Doctors who are torn over how aggressively to treat a cancer patient, not knowing whether a tumor has fully regressed or is coming back, might someday be able to find out just by testing the patient's blood. In a study forthcoming his week in Science Translational Medicine, John Hopkins researchers say they have tested a way to spot the "fingerprint" of cancer--the changes to the DNA inside cells that make up cancerous tumors. Jeffery Schloss of the National Human Genome Research Institute, who wasn't involved in the study,
likened the approach to drawing a map. Sequencing the letters of the genetic code would be akin to plotting every house in a large neighborhood. The Hopkins team was looking only for neighborhoods—in particular, neighborhoods out of place compared with where they would be in normal tissue [Wall Street Journal]
. The researchers in the study looked at tissue from people with ...