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The Creativity of Microbes

Discover how horizontal gene transfer fuels bacterial evolution and antibiotic resistance through gene swapping and networks.

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In my last post, I wrote about how our genes work in networks, much like circuits made of elements wired together in various ways. As genes are accidentally duplicated, mutated, and rewired, old networks can give rise to new ones. It's pretty clear our ancestors could have never become particularly complex if not for this sort of network evolution. As they acquired nerves, muscles, and other tissues, animals needed to organize more and more genes into new circuits. But in saying this I don't mean to imply that single-celled microbes, such as bacteria, live without gene networks. Far from it. In fact, in many ways bacteria are more adept at network engineering than we are. Evolution has engineered the networks of bacteria with many of the same tricks that produced our own. As one bacterium divides into two, all sorts of mistakes can creep into its duplicating DNA. As one ...

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