In tomorrow's New York Times, I have a profile of Arthur Horwich, a medical geneticist who has spent a quarter century trying to figure out the workings of this beautiful molecular box. Today he won the Lasker Award, a prize for medicine that has often gone to scientists who later won the Nobel. Why all accolades for a little box? Because without it, you'd be dead. And as Horwich and others have discovered what goes on inside, they've helped change the way we understand the biology of the cell. Check it out. [Image of GroEL from Molecular Chaperone Group, Birkbeck College]