Register for an account

X

Enter your name and email address below.

Your email address is used to log in and will not be shared or sold. Read our privacy policy.

X

Website access code

Enter your access code into the form field below.

If you are a Zinio, Nook, Kindle, Apple, or Google Play subscriber, you can enter your website access code to gain subscriber access. Your website access code is located in the upper right corner of the Table of Contents page of your digital edition.

Planet Earth

Orangutan Genome: The Orange Apes Evolved at Their Own Quirky Pace

80beatsBy Andrew MosemanJanuary 28, 2011 12:10 AM

Newsletter

Sign up for our email newsletter for the latest science news

orangutan.jpg

Welcome to the family of critters with sequenced genomes, orangutans. In Nature this week, scientists unveil the draft DNA sequencing of our great ape cousins—the only great apes that live exclusively in Asia.

The researchers assembled the draft genome of the female Sumatran orangutan (Pongo abelii) using a whole-genome "shotgun" strategy, an old-fashioned approach that cost about $20 million. In addition, the researchers gathered sequence data from five wild Sumatran orangutans and five Bornean orangutans (Pongo pygmaeus) using a faster and thousandfold cheaper next-generation platform. [LiveScience]

What did scientists find in there? For one thing, orangutans share about 97 percent of the their genome with humans, compared to the 99 percent we famously share with chimpanzees. The two orangutan species—inhabiting the Indonesian islands of Borneo

and Sumatra

—diverged about 400,000 years ago, lead author Devin Locke says. That's much more recently than scientists had thought. They also discovered that over the last 15 million years, orangutan DNA

changed at a different rate than either ours or chimps'. Orangutans have undergone fewer mutations of the DNA, have a lower gene turnover rate, and have fewer duplicated DNA segments.

"That doesn't mean the species itself has evolved more slowly, but that this particular mechanism of genome evolution has been proceeding at a lower rate," Locke said. "Humans and chimps, in sharp contrast, have experienced an acceleration in this form of evolution over the past 5 million years or so." [LiveScience]

That's not the only peculiarity they found:

While in 2004 there were about only 7,000 Sumatran orangutans left in the wild, the researchers found that their population is actually much more genetically diverse than the 50,000 Bornean orangutans in the wild. Why the Sumatran orangutans are so much more genetically diverse is unknown. [USA Today]

As scientists use the new data to sort out the difference between the two remaining orangutan groups—and what their evolution says about all of us primates—they can simultaneously use it to figure out how best to protect them.

Knowing about their genetic diversity can help zoos and conservationists preserve and protect the species, Locke said. For instance, the Borneo and Sumatran species of orangutans should likely not be interbred, and genetically diverse populations are usually more likely to survive. In turn, the study has implications for human health. Inherited diseases are often linked to duplications in the DNA sequence that orangutans lack, Locke said. [Reuters]

Related Content: 80beats: Lice DNA Reveals When Humans First Clothed Their Nakedness

80beats: 4 Messages a Pantomiming Orangutan Might Be Trying to Convey

80beats: An Active Orangutan Burns Fewer Calories Than a Lazy Human

80beats: Study: Orangutans Play Leaf Instruments to Fool Predators

80beats: Syncopated Rhythm Makes Orangutans Masterful Swingers

Image: flickr / ltshears

2 Free Articles Left

Want it all? Get unlimited access when you subscribe.

Subscribe

Already a subscriber? Register or Log In

Want unlimited access?

Subscribe today and save 70%

Subscribe

Already a subscriber? Register or Log In