20 Ideas That Will Rule Research in the Next 20 Years

On the edge of a brave new world.

By Matt Mahurin
Oct 1, 2000 5:00 AMNov 12, 2019 5:19 AM

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The business of science, so to speak, is knowledge. And knowledge is power. Deciding how to handle these new forms of knowledge will be just as important as— and probably far more problematic than— creating the knowledge itself.

Francis S. Collins, geneticist, director of the Human Genome ProjectWith the sequence of the human genome largely determined, laboratory research of human diseases will shift as researchers adopt a "genome attitude" toward solving problems. First, there will be increased emphasis on a systems approach. Researchers will examine the integrated functions among many genes, gain insight into the web of coordinated interactions among cellular pathways, and determine the impact of external factors. The number of potential therapeutic targets will increase dramatically as a consequence.

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