The Imagination Effect: A History of Placebo Power

By Rosie Mestel, Knowable Magazine
May 19, 2021 11:00 PMMay 21, 2021 9:25 PM
Placebo
Perkins tractors, touted as cure-alls, were all the rage at the end of the 18th Century. An early “placebo” trial found they didn't work. This 1802 caricature shows a society lady being treated with a Perkins tractor to cure her “venomous tongue”. (Credit: C. Williams/Wellcome Collection/Knowable Magazine)

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A patient swallows a sugar pill that lacks active medicine, or undergoes “surgery” in which incisions are made but the therapeutic procedure is not performed. And yet pain falls away, nausea recedes, mood lifts. Sometimes, the improvements were going to happen anyway. But other times, what’s at play is the power of the mind to influence the body.

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