Antidepressants may help depression in some people but make it worse for others, according to a new paper.
This is a tough one so bear with me.
Gueorguieva, Mallinckrodt and Krystal re-analysed the data from a number of trials of duloxetine (Cymbalta) vs placebo. Most of the trials also had another antidepressant (an SSRI) as well. And the SSRIs and duloxetine seemed to be indistinguishable so from now on I'll just call it antidepressants vs. placebo as the authors did.
People on placebo got, on average, moderately better over 8 weeks.
