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In World First, Scientists Genetically Modify Human Embryos

Chinese scientists push boundaries with genome editing in human embryos using the CRISPR/Cas9 technique, raising serious ethical concerns.

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Chinese researchers have officially taken science into some uncomfortable territory. Researchers at Sun Yat-sen University in Guangzhou have edited the genomes of human embryos, Nature reported in an exclusive Wednesday. The study, which was published in the journal Protein & Cell, confirms rumors that some scientists were conducting these ethically dubious experiments. The report has scientists sounding a warning call, as reported in Nature:

"I believe this is the first report of CRISPR/Cas9 applied to human pre-implantation embryos and as such the study is a landmark, as well as a cautionary tale," says George Daley, a stem-cell biologist at Harvard Medical School in Boston. "Their study should be a stern warning to any practitioner who thinks the technology is ready for testing to eradicate disease gene."

In the study in question, researchers attempted to replace the gene responsible for a potentially fatal blood disorder called β-thalassaemia. They used a gene ...

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