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Will Drilling a Hole in Your Head Cure Alzheimer's?

Yuri Moskalenko's research suggests trepanation could combat age-related cognitive decline by enhancing cranial compliance.

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One Russian neurophysiologist certainly thinks so—in fact, he's dead set on proving it. New Scientistreports that Yuri Moskalenko, former president of the Sechenov Institute of Evolutionary Physiology and Biochemistry, believes that trepanation—drilling a hole in the skull, once a tool of witch doctors to cure migraines—could help anyone from their mid-40s or older to "slow or even reverse the process of age-related cognitive decline." His reasoning is described as follows:

As we age, the proteins in the brain harden, preventing [the cranial] system from working as it should. As a result, the flow of both blood and cerebrospinal fluid is reduced, impairing the delivery of oxygen and nutrients as well as the removal of waste. Moskalenko's research suggests that this normally begins between the ages of 40 and 50. Moreover, in a study of 42 elderly people with dementia, he found that the severity of their cognitive disorder was strongly ...

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