Synthetic cannabinoids, commonly known as “spice” and “K2,” are substances that mimic the psychoactive chemical compounds present in cannabis. They're commonly used by vulnerable populations, including people experiencing homelessness, and have triggered mass overdoses. Though traditionally advertised as a harmless alternative to marijuana, they can do far more serious damage than their naturally occurring predecessors.
Studies suggest that synthetic cannabinoids can cause acute anxiety, panic and psychosis. These compounds also have high abuse and addiction potential, according to research published in Psychopharmacology this September. Based on data gathered between 2015 and 2016, this study represents the most comprehensive analysis so far of spice withdrawal symptoms and the first to compare their severity with cannabis withdrawals. The crucial finding: continued spice consumption produces worse cravings than cannabis.
The survey data included 284 people who said they had consumed synthetic cannabinoids 10 times or more and made attempts to stop within the previous year. Most respondents noted that their attempts triggered three or more withdrawal symptoms, including insomnia, irritability, despondency and craving — and that these symptoms were serious.
