When two or more types of bacteria meet in the wilds of the human body, they can act unpredictably, abandoning their typical responses to antibiotics. Researchers at the University of Texas at Austin recently observed that bacterial species can “collude” with one another to make treatment with antibiotics more difficult.
Staphylococcus aureus and Pseudomonas aeruginosa commonly co-infect wounds, catheters and lungs of cystic fibrosis patients. Staph is usually harmless, but when it’s in the presence of Pseudomonas … well, things can get more serious.
To understand the bacterial intrigue better, the team needed a way to study the two bacteria together. Bioengineer Jason Shear trapped colonies of each in separate puddles of a cooling (and solidifying) protein liquid. The proteins were photoreactive, bonding together in response to laser light. This allowed Shear to trace ultrathin, mostly transparent walls out of the liquid, and to join them into cages, trapping the ...
