Tibetans not only occupy one of the most extreme locations on Earth, they've been doing it for thousands of years. This week in a study in the journal Science, scientists have for the first time picked out the particular genetic features that allow these people to survive in the low oxygen levels of the Tibetan Plateau, which is around 15,000 feet above sea level. Curiously, the way they have evolved to survive is unlike that of other high-altitude dwellers around the world. The American and Chinese researchers doing the study started by keying on 247 genes that looked like good candidates—they tended to change across populations, and seemed to play a role in controlling a person's blood oxygen level.