FDA Approves Opioid Alternative for Pain Relief That Is Non-Addictive

Because the drug doesn’t target the brain, it has less potential for addiction. Learn why this could help the opioid crisis.

By Paul Smaglik
Jan 31, 2025 10:20 PMMar 21, 2025 4:59 PM
Pain killer
(Credit: Peter Kim/Shutterstock)

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Pain relief without addiction has been a pharmaceutical goal long before the opioid crisis. A newly approved medicine appears to have achieved that.

The U.S. Food and Drug Administration (FDA) approved Journavx to treat short-term pain. The drug, which was developed by Vertex Pharmaceuticals in Boston and tested as a pain treatment following surgeries, targets the nerves near an injury site instead of in the brain.

“It works in a way that is different than previous medications,” says Paul Negulescu, senior vice president at Vertex.

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