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Doug Melton: Crossing Boundaries

Doug Melton's diabetes research aims to use stem cells for insulin production in the pancreas, offering hope for better diabetes management.

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Doug Melton Born: September 26, 1953 Mother: Betty Melton, court reporter Father: A. Melton, grocery store managerPh.D. thesis: Gene injections into amphibian oocytes

Sitting in Doug Melton's Harvard University office on a spring day, I look at the faces of his children in photographs on the desk. Sam is 14 years old now, with short hair and a slightly awkward smile; Emma has long, dark hair and serious eyes. A college freshman, Emma once wrote in an essay that she wants to become an embryologist like her father. "I am also interested in becoming a member of Congress and petitioning for a cure that way," she wrote. Her father says, "I just hope she gets the chance."

Inside Sam and Emma is an immune system that has destroyed cells called islets that are responsible for producing insulin in the pancreas. Insulin is an enzyme that helps transport sugars from the ...

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