Copy number variation in genes

A new paper in Nature, Global variation in copy number in the human genome, suggests that it isn't just SNPs that matter in regards to human variation. Those of you who are "in the know" aren't surprised, so this press release is a bit much. Along with a focus on gene regulation, this is a fascinating new area which expands our understanding of how we are how we are beyond the raw sequence. p-etr at my other blog has a lot more. RPM has a post scheduled on this topic, I saw a preview when he published it to make sure it looked right. The press is making a big deal out of this, so we'll see where it goes.... Addendum: Why does gene copy number matter? The most obvious way is that more gene is proportional to more transcription which results in more translation which results in more final ...