Balancing selection & pigmentation loci

Gene Expression
By Razib Khan
Mar 14, 2008 2:10 PMNov 5, 2019 9:28 AM

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A few days ago I mooted the possibility that balancing selection may be more common than we had assumed, and that much of the recent evolutionary action in our species' history might be characterized by non-fixed allele frequencies which exhibit the signatures of positive selection because of their shallow time depth. I was interested in the idea for an important reason. Below the fold are are a range of data for two loci implicated in skin color variation in human populations; SLC24A5 and SLC45A2.

SLC45A2SLC24A5

Mozabite0.40.87

Bedouin0.230.97

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