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A Second X Chromosome Could Explain Why Women Live Longer Than Men

Discover why longer lifespans in females may be linked to the X chromosome's role in longevity and mouse studies.

Researchers say that women may be born with an advantage when it comes to longevity.Credit: Pressmaster/Shutterstock.com

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Women have an average life expectancy that’s about 4 years longer than men’s – regardless of culture or geography. Even among animal species, females outlive males.

Why females have an advantage in the longevity department hadn’t been well understood. In the past, some had assumed it had to do with lifestyle. But scientists say there may be a genetic mechanism underlying this age-old phenomenon. In a new study, researchers found that mice with two X chromosomes lived longer, regardless of other biological factors. Researchers say the finding suggests the second X chromosome may govern longevity and explain why women outlive men.

All mammals are born with two sex chromosomes. Females have two X chromosomes, whereas males have one X and one Y. X chromosomes are necessary for survival and contain important genes related to the brain. Y chromosomes, on the other hand, are found only in males and are not ...

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