A Common Parasite, Toxoplasma Gondii, Could One Day Deliver Drugs To The Brain

Toxoplasma is often transmitted to people from contaminated food or cat feces.

By Bill Sullivan, Indiana University
Aug 12, 2024 4:00 PM
parasite
(Credit: Dr_Microbe/iStock via Getty Images Plus)

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Parasites take an enormous toll on human and veterinary health. But researchers may have found a way for patients with brain disorders and a common brain parasite to become frenemies.

A new study published in Nature Microbiology has pioneered the use of a single-celled parasite, Toxoplasma gondii, to inject therapeutic proteins into brain cells. The brain is very picky about what it lets in, including many drugs, which limits treatment options for neurological conditions.

As a professor of microbiology, I’ve dedicated my career to finding ways to kill dangerous parasites such as Toxoplasma. I’m fascinated by the prospect that we may be able to use their weaponry to instead treat other maladies.

Microbes as Medicine

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