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Hairless Dogs Give up the Genetic Secret of Their Bald Glory

Explore the genetic secrets behind hairless dog breeds and how the FOXI3 gene mutation influences their unique characteristics.

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Researchers have discovered the gene that determines the baldness of several hairless dog breeds, and say it may

offers new insight into the development of skin and hair in other animals – including humans [New Scientist].

Mexican hairless, Peruvian hairless and Chinese crested dog breeds all share the same mutation, researchers say, which

probably appeared about 4,000 years ago in Mexican hairless dogs and eventually passed through breeding into the other two dog breeds, Leeb says. “It’s extremely improbable that an identical mutation would have arisen three times,” he says [Science News].

In the study, published in Science [subscription required], researchers found

revealed an insertion of seven letters, or base pairs, of genetic code in a gene called FOXI3 in all of the hairless dogs. Although the exact function of the FOXI3 gene is unknown, other genes in the FOX family control embryonic development in mammals. When the researchers investigated ...

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