, a disease whose victims can suffer serious internal bleeding and may bleed to death from injuries, has a long and eventful history. Caused by defective blood clotting factors, the disease has been with us since at least the second century
, when a rabbi gave mothers whose first two sons had bled to death from circumcision wounds permission to leave the third sons uncircumcised. It also famously afflicted several members of European royal families
. But a study
published in the New England Journal of Medicine brings us a bit closer to a new kind of historic event: a cure. Following up on years of preclinical trials, including the curing of hemophiliac mice earlier this year
, scientists gave six patients a gene therapy
treatment, injecting them with a specially built virus carrying a functioning version of the gene for the defective clotting factor. The virus inserted the ...