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Evolution's gears don't reverse easily

Evolutionary adaptations can be reversed, but it's rare according to new research on drug-resistance gene adaptations.

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Evolutionary Adaptations Can Be Reversed, but Rarely:

Physicists' study of evolution in bacteria shows that adaptations can be undone, but rarely. Ever since Charles Darwin proposed his theory of evolution in 1859, scientists have wondered whether evolutionary adaptations can be reversed. Answering that question has proved difficult, partly due to conflicting evidence. In 2003, scientists showed that some species of insects have gained, lost and regained wings over millions of years. But a few years later, a different team found that a protein that helps control cells' stress responses could not evolve back to its original form.

Here are the primary results:

They found that a very small percentage of evolutionary adaptations in a drug-resistance gene can be reversed, but only if the adaptations involve fewer than four discrete genetic mutations. The findings will appear in the May 13 issue of the journal Physical Review Letters. Lead authors of the ...

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